I had the same problem in hellfire turns out the option you choose to play resident evil 4 up to hellfire are no good from that point on so on 3d-analyze unselect all options and choose hw tnl and sw tnl thats it. Since I did that i'm a very happy camper and about to finish the game. If you see this forum you'll see I had the same problem.

Also Need Help on Chapter 4 game just goes black and dies to windows WTF!!!!! played fine all the way up to that part got a ati radeon 9200se