The following issues are most annoying with MesaFX in UT2004:

- The Squares instead of test is due to the missing render to texture capability I guess. I also can see such white squares in other programs. f.e. try the 'Variform' Demo or similar stuff.
- The many Texture Layers make the world look very rastered.
- The Screen Size is not adjusted correctly, only 640x480 are visible from the lower left corner of the whole screen.

I think the first issue may be possible to be emulated by mesafx, the last issue seems to be some bug?
A visible 1024x768 resolution would be fine on a V2 SLI

Ciao...